专利名称:8-substituted-2,6-methano-3-benzazocines
and 3-substituted morphinanes as opioidreceptor binding agents
发明人:Wentland, Mark P.申请号:EP08004779.8申请日:20011031公开号:EP1944292B1公开日:20160217
摘要:8-Substituted-2,6-methano-3-benzazocines of general structure I in which A is -CH2-OH, -CH2NH2, -NHSO2CH3, and Y is O, S, NR<17> or NOH bind to opioid receptorsand are useful as analgesics, anti-diarrheal agents, anticonvulsants, antitussives and anti-addiction medications. 8-Carboxamides, thiocarboxamides, hydroxyamidines andformamides are preferred.
申请人:RENSSELAER POLYTECH INST
地址:US
国籍:US
代理机构:Graf von Stosch, Andreas
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