专利名称：ESTIMATION OF PROTEIN-COMPOUND
INTERACTION AND RATIONAL DESIGN OFCOMPOUND LIBRARY BASED ON CHEMICALGENOMIC INFORMATION
发明人：OKUNO, YASUSHI,TANEISHI,
KEI,TSUJIMOTO, GOZOH
申请号：EP07744170申请日：20070525公开号：EP2031528A4公开日：20090617
摘要：Its purpose is rationally and effectively screening compounds. This problem canshow the space coordinates of second group of chemicals by the first compound andsecond space for limiting the first space representation space coordinates group, and theuse to the conversion of the first space of the coordinate and second space coordinate tomap with technology is selected from multivariate analytical technique, learning by roteand above-mentioned method of equal value, so that first group of chemicals is to becharacterized in that fisrt feature amount, while the 2nd 1 group of chemicals ischaracterized in that correlation between second feature and above-mentioned firstspace and second space reach maximum. Specifically, a kind of system, the mode and onegroup of compound mechanical study biological information (protein sequence relevantto the amount of characteristic is used wherein to interact between a histone matter,express data etc.) (chemical information is about chemical structure for the amount ofcharacteristic and compound, physical property etc.) be statistics pattern with interact on
the basis of estimate it is identical, solves the above problem, as described above.
申请人：KYOTO UNIVERSITY
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