专利名称:MICROBUBBLE COMPLEXES AND METHODS
OF USE
发明人:Praveena Mohan,Anup Sood,James Edward
Rothman,John Donald Burczak,Hae WonLim,Lisa Anne Lowery
申请号:US15219419申请日:20160726
公开号:US20170007636A1公开日:20170112
专利附图:
摘要:The present invention relates to a microbubble complex comprising a
microbubble having an outer shell comprising a mixture of native and denatured albuminencapsulating a perfluorocarbon gas, a therapeutic agent, a bifunctional linker having oneend attached to the therapeutic agent and the other attached to a ligand and whereinthe ligand is bound to the other shell of the microbubble through hydrophobic
interactions. Also included are methods for delivering the aforementioned microbubblecomplex to a tissue target.
申请人:General Electric Company
地址:Schenectady NY US
国籍:US
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