Synthetic melanin

专利名称：Synthetic melanin发明人：JOHN M PAWELEK申请号：AU7958394申请日：19940926公开号：AU7958394A公开日：19950501

摘要：A melanin that is soluble in an aqueous solution at a pH between 5 and 9 at atemperature of 0 to 100 DEG C. Advantageously, the melanin is capable of being filteredthrough at least a 0.45 micron size filter, and has a molecular weight of greater than10,000 kilodaltons. The melanin is useful for providing a naturally-appearing tan tomammalian skin and hair. Such melanin can be produced by combining dopachrome andan appropriate enzyme, or by incubating 5,6-dihydroxyindole-2-carboxylic acid alone orwith 5,6-dihydroxyindole, or with 3-amino-tyrosine. The melanin is also useful for

providing a sun-screen to mammalian skin and hair, to treat post-inflammatory hypo- andhyperpigmentation, to tint glass and plastic, to protect industrial materials againstultraviolet damage, and as a coloring agent in foodstuffs such as coffee, tea, soda, whiskyand liquors. Also included are self-tanning compositions containing melanin and DHA.

申请人：YALE UNIVERSITY

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